DOSING OPTIONS TO INDIVIDUALIZE PATIENT CARE1

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Not an actual patient.

Choose the dosing schedule that’s right for each of your patients with advanced prostate cancer.1

Four In-Office Dosing Options1

Dosing in nonmetastatic disease

In patients treated GnRH analogues for prostate cancer, treatment is usually continued upon development of nonmetastatic and metastatic castration-resistant prostate cancer.1

6 month

45-mg injection every 6 months

2x per year

4 month

30-mg injection every 4 months

3x per year

3 month

22.5-mg injection every 3 months

4x per year

1 month

7.5-mg injection every month

12x per year
injection-kit

All doses of LUPRON DEPOT come in a complete injection kit with everything needed for administration.1

GnRH=gonadotropin-releasing hormone.

An All-In-One Syringe

Safety Considerations

Injection site reactions and injection site pain/discomfort were experienced in clinical trials.1

*Mechanically prohibits the transfer of environmental contaminants into the system and the escape of hazardous drug or vapor concentrations outside the system.4

Learn How to Mix and Administer LUPRON DEPOT

Download and print step-by-step mixing and administering instructions.

Because the dual-chamber syringe requires no external mixing, all mixing takes place within the prefilled syringe in 3 steps.1*

*Reconstitution and administration for injection of LUPRON DEPOT requires a total of 10 steps; of those, only 3 are for suspension mixing.

*Adapted from Section 2.5, steps 2-4 of the LUPRON DEPOT package insert:

step1
Screw in plunger

To prepare for injection, screw the white plunger into the end stopper until tile stopper begins to turn.

step2
Release diluent

Hold the syringe UPRIGHT. Release the diluent by SLOWLY PUSHING (6 to 8 seconds) the plunger until the first middle stopper is at the blue line in the middle of the barrel.

step3
Mix powder

Keep the syringe UPRIGHT. Mix the microspheres (powder) thoroughly by gently shaking the syringe until the powder forms a uniform suspension. The suspension will appear milky. If the powder adheres to the stopper or caking/clumping is present, tap the syringe with your finger to disperse. DO NOT USE if any of the powder has not gone into suspension.1

Delivering Treatment for aPC

“LUPRON DEPOT has been a pioneer in the treatment of advanced prostate cancer by creating multiple dosing options and by developing delivery system innovations.”

aPC=advanced prostate cancer.