Lucas, age 64
Semiretired financial analyst, passionate cook,
husband, father
Not an actual patient.
Choose the dosing schedule that’s right for each of your patients with advanced prostate cancer. Four in-office dosing options help you meet individual patient needs and schedule regular monitoring.
Four In-Office Dosing Options
2019 label update: Dosing in nonmetastatic disease
The dosage and administration information in the Prescribing Information for LUPRON DEPOT was amended to include continuation of treatment upon development of nonmetastatic castration-resistant prostate cancer1
Dosing in non-metastatic disease
In patients treated with GnRH analogues for prostate cancer, treatment is usually continued upon development of non-metastatic and metastatic castration-resistant prostate cancer.1
![](/content/dam/lupronhcpivy/images/dosing-options/Desktop/4_GrillingPatient_Solo.png)
Learn How to Mix and Administer LUPRON DEPOT
Download and print step-by-step mixing and administering instructions.
Because the dual-chamber syringe requires no external mixing, all mixing
takes place within the prefilled syringe in 3 steps.1*
*Reconstitution and administration for injection of LUPRON DEPOT requires a
total of 10 steps; of those, only 3 are for suspension mixing.
*Adapted from section 2.5, steps 2-4 of the LUPRON DEPOT package insert:
![](/content/dam/lupronhcpivy/images/dosing-options/Desktop/4_Icon_Mix_Step1@2x.png)
To prepare for injection, screw the white plunger into the end stopper until the stopper begins to turn.
![](/content/dam/lupronhcpivy/images/dosing-options/Desktop/4_Icon_Mix_Step2@2x.png)
Hold the syringe UPRIGHT. Release the diluent by SLOWLY PUSHING (6 to 8 seconds) the plunger until the first middle stopper is at the blue line in the middle of the barrel.
![](/content/dam/lupronhcpivy/images/dosing-options/Desktop/4_Icon_Mix_Step3@2x.png)
Keep the syringe UPRIGHT. Mix the microspheres (powder) thoroughly by gently shaking the syringe until the powder forms a uniform suspension. The suspension will appear milky. If the powder adheres to the stopper or caking/clumping is present, tap the syringe with your finger to disperse. DO NOT USE if any of the powder has not gone into suspension.1
"LUPRON DEPOT has been a pioneer in the treatment of advanced prostate cancer by creating multiple dosing options and by developing delivery system innovations."