COMMITMENT TO CARE TRUSTED SINCE 19851*

Not an actual patient.

LUPRON DEPOT, an androgen deprivation therapy (ADT), has been a pioneer in the treatment of advanced prostate cancer.1

A Wealth of Experience

40 Years

The most clinical experience of any GnRHa on the market1*

Millions of injections administered3‡

*FDA approved in 1985, the first GnRHa for the treatment of advanced prostate cancer patients.1

Based on IQVIA NSP data as of February 2025.

Based on MEU sales data as of 2017-2022.

GnRHa=gonadotropin-releasing hormone agonist.

A Number of Firsts

From day 1, LUPRON DEPOT has been committed to the treatment of advanced prostate cancer.

1985

First drug in its class approved for the treatment of advanced prostate cancer1

1989

First and only GnRHa prefilled dual-chamber syringe. No external mixing required. Flexible dosing options4-11

2007

Launched LuproLink Inventory Management System

2014

Support PLUS Program launched: A program that supports your patients with benefits verification and reimbursement support

2016

Dosage and administration section of the label updated to include continued treatment in patients who develop metastatic CRPC4,11

2019

Dosage and administration section of the label updated to include continued treatment in patients who develop nonmetastatic or metastatic CRPC4,11

2022

LUPRON DEPOT is indicated for treatment of advanced prostate cancer4

CRPC=castration-resistant prostate cancer.

Coverage

We are committed to making LUPRON DEPOT accessible to patients.

>99 % of lives

LUPRON DEPOT is covered for >99% of lives with national commercial insurance, Medicaid, and Medicare Part B combined12*†

~100 % covered

LUPRON DEPOT is covered by ~100% of Medicare Part B plans12*†

Overview of Medicare Part B and D

Medicare

Part B

Most LUPRON DEPOT patients are covered through Medicare Part B12

Part B is a medical benefit that covers services such as in-office administration for medications like LUPRON DEPOT

Part B may offer lower out-of-pocket costs for patients compared with Part D or commercial pharmacy benefits

Medicare

Part D

Part D is a prescription drug benefit that covers medications dispensed through a pharmacy

Part D may have higher out-of-pocket costs
than Part B

Source: Managed Markets Insight and Technology, LLC, a trademark of MMIT, as of September 2023. This analysis reflects medical insurance coverage only.

*For those national commercial and Medicare plans that report coverage data; excludes plans and payors with unknown coverage.

Coverage requirements and benefit designs vary by payor and may change over time. Please consult with payors directly for the most current reimbursement policies.

“...decades of experience in using LUPRON DEPOT in my practice continues to reinforce my confidence in prescribing it as my first choice for patients with advanced prostate cancer.”