Understanding Your
Prostate Cancer Diagnosis

A diagnosis of prostate cancer may make you feel completely overwhelmed. But you’re not alone. Prostate cancer is one of the most frequently diagnosed cancers in American men—but early detection can improve your ability to manage the disease. The information on this website can help you gain a better understanding of your prostate cancer diagnosis and guide you through how it can be treated with Lupron Depot.1

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Treating Advanced Prostate
Cancer with Lupron Depot

Lupron Depot is the #1 prescribed drug in its class in the US* for the treatment of advanced prostate cancer. Although it’s not a cure, Lupron Depot suppresses the testosterone that causes testosterone-dependent prostate cancer cells to grow. Following your treatment plan and getting monitored regularly to check your progress can help you get the best results from your Lupron Depot therapy.2,3

Learn More *Based on IMS Health for the US GnRHa market.

Is Lupron Depot Covered
by My Insurance?

Lupron Depot is covered by most insurance carriers and Medicare. If you have any concerns about your insurance coverage, be sure to talk with a member of your treatment team. There are also several programs available to help cover costs.

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  • Learn More

    How is prostate
    cancer diagnosed?
    Learn how tests such
    as a prostate-specific
    antigen (PSA) test can
    help physicians diagnose
    prostate cancer. Learn more

  • Learn More

    How does Lupron Depot work to treat prostate cancer? Lupron Depot suppresses testosterone, but does not cure prostate cancer.3 Learn more

  • Learn More

    Tips for talking with your treatment team It helps to know what to ask before you talk with your treatment team about your prostate cancer diagnosis. Print these helpful tips for a quick reference. Learn more

  • Do Not Take If
    • You should not take LUPRON DEPOT if you have had any type of allergic reaction to LUPRON DEPOT or similar drugs.
    • Females who are or may become pregnant should not receive any formulation of LUPRON DEPOT.

    Reference:
    LUPRON DEPOT 7.5 mg for
    1–month, 22.5 mg for 3–month,
    30 mg for 4–month, and 45 mg for 6–month [package insert].

  • Before Starting
    • Talk to your doctor about your medical history and all other medicines that you take.
    • Increased risk of heart attack, sudden death, and stroke can occur in men using LUPRON DEPOT. Discuss this increased risk with your doctor before starting treatment and report any new symptoms during treatment.
    • Long-term use of LUPRON DEPOT can affect the electrical activity of your heart. Your doctor must determine if the benefits of using LUPRON DEPOT outweigh the risks, especially if you have congenital long QT syndrome, abnormal blood tests for electrolytes, congestive heart failure, or if you take medications to regulate your heartbeat.
    • Convulsions have been observed in patients taking leuprolide acetate, including patients who have a history of seizures, epilepsy, or brain disorders (related to blood vessels, nerves, or tumors), and in those taking medications associated with convulsions. Convulsions have also been reported in patients without any of these conditions.

    Reference:
    LUPRON DEPOT 7.5 mg for
    1–month, 22.5 mg for 3–month,
    30 mg for 4–month, and 45 mg for 6–month [package insert]

  • What to Expect
    • LUPRON DEPOT causes an increase in testosterone during the first few weeks of therapy.
      • Some men may experience temporary new or worsening symptoms of prostate cancer, including urinary symptoms and/or bone pain.
      • If your cancer has spread to the spine or urinary tract, urinary blockage or pressure on the spine may occur and can sometimes lead to paralysis, which may be life-threatening.
      • You may require close medical attention during the first few weeks of therapy. Notify your doctor if you develop any new or worsened symptoms after beginning LUPRON DEPOT treatment.
    • High blood sugar and increased risk of diabetes can occur in men using LUPRON DEPOT. Your doctor will monitor your blood sugar during treatment.
    • Regular blood tests are needed to check your testosterone and prostate-specific antigen (PSA) levels.
    • LUPRON DEPOT may cause impotence.

    Reference:
    LUPRON DEPOT 7.5 mg for
    1–month, 22.5 mg for 3–month,
    30 mg for 4–month, and 45 mg for 6–month [package insert]

  • Side Effects
    • The most common side effects of LUPRON DEPOT include hot flashes/sweats; injection site reaction/pain; general pain; swelling; testicular shrinkage; difficulty urinating; fatigue/weakness; headache; and joint, gastrointestinal, and respiratory problems.

    For more information, talk with your healthcare provider.

    Reference:
    LUPRON DEPOT 7.5 mg for
    1–month, 22.5 mg for 3–month,
    30 mg for 4–month, and 45 mg for 6–month [package insert]

  • Helpful Resources

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

    If you cannot afford your medication, contact www.pparx.org or call the toll-free phone number (1-888-4PPA-NOW) for assistance.

    View the full Prescribing Information for LUPRON DEPOT at http://www.rxabbvie.com/pdf/
    lupron7_5mg.pdf
    and http://www.rxabbvie.com/pdf/
    lupron3_4_6month.pdf
    .

    Reference:
    LUPRON DEPOT 7.5 mg for
    1–month, 22.5 mg for 3–month,
    30 mg for 4–month, and 45 mg for 6–month [package insert].

Print
Safety Facts
  • LUPRON DEPOT 7.5 mg for 1–month, 22.5 mg for 3–month, 30 mg for 4–month, and 45 mg for 6–month administration are prescribed for the palliative treatment of advanced prostate cancer.
  • LUPRON DEPOT is a prescription medication that must be administered in your doctor’s office.
Reference:
LUPRON DEPOT 7.5 mg for 1–month, 22.5 mg for 3–month, 30 mg for 4–month, and 45 mg for 6–month [package insert]

References:

  1. American Cancer Society Web site. Prostate cancer—detailed guide. Available at: http://www.cancer.org/Cancer/prostate
    cancer/detailedguide/index
    . Accessed July 27, 2012.
  2. Data on file, AbbVie Inc.
  3. Lupron Depot® [package inserts].